Domagk, Gerhard Johannes Paul

SUBJECT AREA: Medical technology
b. 30 October 1895 Lagow, Brandenburg, Germany
d. 24 April 1964 Burgberg, Germany
German physician, biochemist and pharmacologist, pioneer of antibacterial chemotherapy.
Domagk's studies in medicine were interrupted by the outbreak of the First World War and his service in the Army, delaying his qualification at Kiel until 1921. For a short while he worked at the University of Greifswald, but in 1925 he was appointed Reader in Pathology at the University of Munster, where he remained as Extraordinary Professor of General Pathology and Pathological Anatomy (1928) and Professor (1958).
In 1924 he published a paper on the role of the reticulo-endothelial system against infection. This led to his appointment as Director of Research by IG Farbenindustrie in their laboratory for experimental pathology and bacteriology. The planned programme of research into potential antibacterial chemotherapeutic drugs led, via the discovery of the dye Prontosil rubrum by his colleagues, to his reporting in 1936 the clinical antistreptococcal effects of the sulphonamide drugs. These results were confirmed in other countries, but owing to problems with the Nazi authorities he was unable to receive until 1947 the Nobel Prize that he was awarded in 1939.
Domagk turned his interest to the chemotherapy of tuberculosis, and in 1946 he was able to report the therapeutic activity of the thiosemicarbazones, which, although too toxic for general use, in their turn led to the discovery of the potent and effective isoniazid. In his later years he moved into the field of cancer chemotherapy, but interestingly he wrote, "One should not have too great expectations of the future of cytostatic agents." His only daughter was one of the first patients to have a severe streptococcal infection successfully treated with Prontosil rubrum.
Principal Honours and Distinctions
Nobel Prize for Medicine 1939. Foreign Member of the Royal Society. Paul Ehrlich Gold Medal.
1935, "Ein Beitrag zur Chemotherapie der bakteriellen Infektionen", Deutsche med. Woch.
1924, Virchows Archiv für Path. Anat. und Physiol. u.f. klin. Med. 253:294–638.
Further Reading
1964, Biographical Memoirs of the Royal Society: Gerhard Domagk, London.

Biographical history of technology. - Taylor & Francis e-Librar. . 2005.

Look at other dictionaries:

  • Medizinnobelpreis 1939: Gerhard Johannes Paul Domagk —   Der deutsche Bakteriologe wurde für den Nachweis der antibakteriellen Wirkung der Sulfonamide ausgezeichnet, mit dem er der Chemotherapie einen entscheidenden Impuls gab.    Biografie   Gerhard …   Universal-Lexikon

  • Domagk — Gerhard Johannes Paul Domagk (* 30. Oktober 1895 in Lagow, Brandenburg; † 24. April 1964 in Königsfeld im Schwarzwald) war ein deutscher Pathologe und Bakteriologe. Inhaltsverzeichnis 1 Leben 2 Auszeichnungen (Auswahl) …   Deutsch Wikipedia

  • Gerhard Domagk — Born 30 October 1895 Lagow, Brandenburg Died 24 April 1964 (aged 68) Burgberg …   Wikipedia

  • Gerhard Domagk — Nombre Gerhard Johannes Paul Domagk Nacimiento …   Wikipedia Español

  • Gerhard Domagk — Gerhard Johannes Paul Domagk (* 30. Oktober 1895 in Lagow, Brandenburg; † 24. April 1964 in Königsfeld im Schwarzwald) war ein deutscher Pathologe und Bakteriologe und Nobelpreisträger. Inhaltsverzeichnis 1 Leben 2 Auszeichnungen (Auswahl) …   Deutsch Wikipedia

  • Gerhard Domagk — Naissance 30 octobre 1895 Lagow, Brandebourg (Allemagne) Décès 24 April 1964 Burgberg (Allemagne) Nationalité allemande …   Wikipédia en Français

  • Gerhard Domagk — Gerhard Johannes Paul Domagk (n. Lagow, Brandeburgo, 30 de octubre de 1895 † Burgberg, 14 de abril de 1964) fue un patólogo y bacteriólogo alemán que obtuvo el Premio Nobel de Fisiología o Medicina en 1939. Estudió medicina en la Universidad de… …   Enciclopedia Universal

  • Liste der Biografien/Dom–Dop — Biografien: A B C D E F G H I J K L M N O P Q …   Deutsch Wikipedia

  • Medical technology — See also: INDEX BY SUBJECT AREA [br] Abel, John Jacob Arsonval, Jacques Arsène d Auenbrugger, Leopold Elder von Berger, Hans Bovie, William Brunschwig, Hieronymus Bunch, Cordia C …   Biographical history of technology

  • Домагк, Герхард — Герхард Йоханнес Пауль Домагк нем. Gerhard Johannes Paul Domagk …   Википедия

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”

We are using cookies for the best presentation of our site. Continuing to use this site, you agree with this.